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Milestones around MCW Proteomics Center

February 12, 2005:  DeNovoID tool released

DeNovoID is a program that has been specifically designed to use degenerate amino acid sequence and mass data derived from MS experiments to search a peptide database. Since the algorithm employed depends on the amino acid composition of the peptide and not its sequence, DeNovoID does not have to consider all possible sequences, but rather a smaller number of compositions consistent with a spectrum. DeNovoID also uses a geometric indexing scheme that reduces the number of calculations required to determine the best peptide match in the database. The user selects a database to search and inputs data for a series of peptides consisting of ordered sequence tags, non-ordered sequence tags, and mass tags in the following format:
 
    >header line
    ORDEREDSEQUENCE[NONORDREDSEQUENCE][200.4]
 
The DeNovoID program then searches the database for near and exact matches and emails the results to the user.
 

January 20, 2005:  Animal Models & Experimental Systems Component updated

Component 2 - Animal Models & Experimental Systems - updated Protocols and some cell photographs.
 

July 23, 2004:  Component 3 added Elisa Data Reports pages

Component 3 added Elisa Data Reports pages. Click for details.
 

September 17, 2003:  Component 2 is available online

Animal Models & Experimental Systems Component is available online. Its overall task is to develop, maintain and produce animal and cell culture models of angiogenesis for analysis. Click for details.
 

July 12, 2003:  Component 3 is available online

Protein Analysis and Technology Implementation Component is available online. You can visit it to get its goals, milestones, methods and members. Click for details.
 

October 12, 2002:  MCW receives $15.6 million contract to fathom role of proteins in disease

The Medical College of Wisconsin has received a seven-year, $15.6 million contract, the largest in its history, to help develop new technologies to understand the critical role proteins play in health and disease.
Click for details.
 

October 09, 2002:  NHLBI Press Release

The National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health, has launched a major initiative to develop innovative proteomic technologies by creating 10 special centers of research, each funded for 7 years.
Click for more details.

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